Functionalized magnetic nanosystems for diagnostic tools and devices: New perspectives in disease diagnosis
Kitapta bölümler > Araştırma Kitabı · 2024
Yazarlar: Faezeh GHORBANIZAMANI, Hıchem MOULAHOUM, Figen ZİHNİOĞLU, Suna TİMUR
Functionalized Magnetic Nanosystems for Diagnostic Tools and Devices: Current and Emerging Research Trends, Araştırma Kitabı, Elsevier BV, B, Uluslararası, 2024, ss 171-205, Hollanda, amesterdam
DOI: https://doi.org/10.1016/B978-0-443-19012-4.00009-6
Özet
<p><span style="color: rgb(31, 31, 31);">Scientists have long sought more practical technologies using alternative materials in various fields. Since its inception, nanotechnology has garnered significant interest and enabled rapid progress in development. In the medical field, the early, sensitive, and quantitative characterization of biomarkers has been a priority for the early diagnosis and treatment of numerous diseases. In recent decades, engineered inorganic </span><a href="https://www.sciencedirect.com/topics/materials-science/nanoparticle" rel="noopener noreferrer" target="_blank" style="color: rgb(31, 31, 31); background-color: rgba(0, 0, 0, 0);">nanoparticles</a><span style="color: rgb(31, 31, 31);"> have greatly advanced this field and have been used successfully in theranostic applications. As a result, there has been a growing focus on magnetic nanosystems, such as particles, wires, and tubes, due to their abilities, including in vivo deep magnetic targeting, magnetic resonance imaging, point-of-care diagnostics, chemotherapy, hyperthermia, bioseparation, and </span><a href="https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/controlled-drug-release" rel="noopener noreferrer" target="_blank" style="color: rgb(31, 31, 31); background-color: rgba(0, 0, 0, 0);">controlled drug release</a><span style="color: rgb(31, 31, 31);">. The modification of magnetic </span><a href="https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/nanomaterial" rel="noopener noreferrer" target="_blank" style="color: rgb(31, 31, 31); background-color: rgba(0, 0, 0, 0);">nanomaterials</a><span style="color: rgb(31, 31, 31);"> through functionalization and decoration has expanded their range of applications, increasing their stability, </span><a href="https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/biocompatibility" rel="noopener noreferrer" target="_blank" style="color: rgb(31, 31, 31); background-color: rgba(0, 0, 0, 0);">biocompatibility</a><span style="color: rgb(31, 31, 31);">, and encapsulation capabilities. This chapter focuses on recent developments in magnetic nanosystems, highlighting the functionalization processes using various organic and inorganic biomoieties. Additionally, it discusses the potential of magnetic nanosystems and their derivatives for magnetic detection in biomedical diagnostics. Finally, it considers the main limitations and concerns in using magnetic nanosystems and future prospects for improving their performance in diagnostic applications.</span></p>