A novel predictor in acute kidney injury: Neutrophil to lymphocyte count

Devrim BOZKURT; Aslı KILAVUZ; Mehmet Berktaş; Selahattin Fehmi AKÇİÇEK

doi:10.19161/etd.414355

A novel predictor in acute kidney injury: Neutrophil to lymphocyte count

Articles > Article · 2018

Authors: Devrim BOZKURT, Aslı KILAVUZ, Mehmet Berktaş, Selahattin Fehmi AKÇİÇEK

Ege Tıp Dergisi, Refereed Journals of Other Institutions, International, Scopus, 2018, vol 57, pp 8-13

DOI: 10.19161/etd.414355

Summary

Aim: Acute Kidney injury (AKI) represents a clinical condition reflecting systemic inflammation. Neutrophil-to lymphocyte ratio (NLR) is novel prognostic marker in various inflammatory conditions. In this retrospective cohort we evaluated two hundred and thirteen AKI patients.  Materials and Methods: The patients’ baseline values on admission, final values at discharge and after discharging during follow-up period in outpatient clinic until six months to one year were recorded. NLR change during follow-up period after hospitalization was also examined. Results: It has been shown that, final NLR and timely changed NLR during hospital course are significant mortality predictors in AKI patients both in univariate and mutually adjusted multivariate logistic regression analysis. To predict mortality, we showed that, level of 9.90 point for final NLR has 73% sensitivity and 87% specifity as compared to value below in ROC analysis (HR: 7.31, CI 3.36-15.91; p<0.001). Conclusion: NLR may be a novel screening tool on patiens' mortality for AKI patients during their hospital course.

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