Use of Esophageal Impedance beyond Diagnosis of GERD
Makaleler > Tam Makale · 2017
Yazarlar: Rukiye VARDAR
Gastroenterology & Hepatology: Open Access, Diğer Kurumların Hakemli Dergileri, Uluslararası, 2017, cilt 6
DOI: 10.15406/ghoa.2017.06.00208
Özet
Combined multichannel intraesophageal impedance-pH (MII-pH) monitoring is currently the the gold standard method to diagnosis of gastroesophageal reflux disease (GERD).A standard MII-pH catheter has six pairs of impedance electrodes.Multiple impedancemeasuring within the esophagus allows determination of direction of bolus movement within the esophagus.So that MII is used as a good esophageal functional test in the diagnosis of swallow, belching, aerophagia and regurgitation.Baseline impedance value has been considered is a marker of transepithelial resistance measured in vitro, which is indicating esophageal epithelial integrity.It has been shown that distal baseline impedance values are correlated with esophageal acid exposure in GERD patients.In addition, baseline impedance values has been studied in the patients with disorders rather than GERD such as eosinophilic esophagitis, esophageal motor disorders and effect of radiofrequency ablation treatment in Barrett's esophagus.In this article, MII-pH is reviewed its clinical applications beyond the diagnosis of GERD.