The state of lipid peroxidation and antioxidants following thrombolytic therapy with rt-PA and streptokinase in acute myocardial infarction
Makaleler > Tam Makale · 1999
Yazarlar: D Ozmen, Bahar BOYDAK, Mehmet Işıl MUTAF, Mehdi ZOGHİ, K Kumanlioglu, I Guner, O Bayindir
JAPANESE HEART JOURNAL, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 1999, cilt 40, ss 267-273
DOI: 10.1536/jhj.40.267
Özet
The role of reactive oxygen products in myocardial damage caused by ischemia-reperfusion has been established in a number of studies performed in animals models. However, studies showing the development of increased free radicals following effective myocardial reperfusion in humans are scarce. In the present study, both the increase of lipid peroxidation (LPO) following early stage thrombolytic therapy which is the current treatment issue performed after acute myocardial infarct (AMI) and the plasma levels of vitamin E and C (chain braker antioxidants) were investigated parallel to time.