Controlled release of curcumin from poly(HEMA-MAPA) membrane
Makaleler > Tam Makale · 2016
Yazarlar: Müşerref Caka, Ceren Türkcan, Deniz Aktaş Uygun, Murat Uygun, Sinan Akgöl, Adil Denizli
Artificial Cells, Nanomedicine, and Biotechnology, Uluslararası, Wos, 2016, cilt 45, ss 426-431
DOI: 10.3109/21691401.2016.1160913
Özet
In this work, poly(HEMA-MAPA) membranes were prepared by UV-polymerization technique. These membranes were characterized by SEM, FTIR, and swelling studies. Synthesized membranes had high porous structure. These membranes were used for controlled release of curcumin which is already used as folk remedy and used as drug for some certain diseases and cancers. Curcumin release was investigated for various pHs and temperatures. Optimum drug release yield was found to be as 70% at pH 7.4 and 37 °C within 2 h period. Time-depended release of curcumin was also investigated and its slow release from the membrane demonstrated within 48 h.