2000bp Upstream of STEAP Genes
Articles > Article ยท 2024
Authors: Ceren Gonen
Applied Sciences Research Periodicals, International, 2024, vol 2, pp 84-89
DOI: 10.63002/asrp.29.675
Summary
Prostate cancer is the most commonly diagnosed cancer and the second leading cause of cancer mortality in men in the Western World. The effects of androgens are mediated by the Androgen Receptor (AR). Therefore, studies focus on the identification of AR-regulated genes that are also highly expressed in the prostate. STAMP family genes STAMP1/STEAP2 and STAMP2/STEAP4 have only expressed in androgen receptor-positive cells, the role of AR in STAMP family gene expression is an important question.