Phytochemical investigation of Scabiosa sicula guided by a preliminary HPLC-ESIMSn profiling
Articles > Article · 2020
Authors: HİLAL KILINÇ, Milena Masullo, Gilda D'Urso, Tamer KARAYILDIRIM, Özgen ALANKUŞ, Sonia Piacente
Phytochemistry, Journal Indexed in SCI Expanded, International, WoS, 2020, vol 174, pp 112350-112350
DOI: 10.1016/j.phytochem.2020.112350
Summary
The genus Scabiosa (Caprifoliaceae) is represented by 80 species, widely used as medicinal plants for their positive effects on human diseases. On the basis of the interesting biological activity shown by Scabiosa spp., the phytochemical investigation of Scabiosa sicula L., never investigated before, was carried out. An initial LC-MS profile of the MeOH extract of S. sicula whole plant guided the isolation of 34 compounds, of which the structures were unambiguously elucidated by NMR analysis as phenolic compounds and triterpene saponins, among which eight undescribed compounds.