Phytochemical investigation of Scabiosa sicula guided by a preliminary HPLC-ESIMSn profiling

Makaleler > Tam Makale · 2020

Yazarlar: HİLAL KILINÇ, Milena Masullo, Gilda D'Urso, Tamer KARAYILDIRIM, Özgen ALANKUŞ, Sonia Piacente

Phytochemistry, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2020, cilt 174, ss 112350-112350

DOI: 10.1016/j.phytochem.2020.112350

Özet

The genus Scabiosa (Caprifoliaceae) is represented by 80 species, widely used as medicinal plants for their positive effects on human diseases. On the basis of the interesting biological activity shown by Scabiosa spp., the phytochemical investigation of Scabiosa sicula L., never investigated before, was carried out. An initial LC-MS profile of the MeOH extract of S. sicula whole plant guided the isolation of 34 compounds, of which the structures were unambiguously elucidated by NMR analysis as phenolic compounds and triterpene saponins, among which eight undescribed compounds.

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