Ailesel akdeniz ateşinde görülebilen diğer bulgular: vaskülitler ve uzamış febril miyalji

Makaleler > Derleme · 2017

Yazarlar: Figen YARGUCU ZİHNİ, Gökhan KESER

Türkiye Klinikleri Romatoloji Özel Sayısı, SCI Expanded İndekslerine Giren Dergi, Uluslararası, TR Dizin (Ulakbim), 2017, cilt 10

Özet

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Priority="33" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Book Title"></w:LsdException> <w:LsdException Locked="false" Priority="37" Name="Bibliography"></w:LsdException> <w:LsdException Locked="false" Priority="39" QFormat="true" Name="TOC Heading"></w:LsdException> </w:LatentStyles> </xml><![endif]--><!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Normal Tablo"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin-top:0cm; mso-para-margin-right:0cm; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0cm; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-fareast-language:EN-US;} </style> <![endif]--><b><span style="font-size:10.0pt;line-height:115%; font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin;color:#222222;background:white;mso-ansi-language: TR;mso-fareast-language:EN-US;mso-bidi-language:AR-SA">Özet: </span></b><span style="font-size:10.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;; mso-fareast-font-family:Calibri;mso-fareast-theme-font:minor-latin;color:#222222; background:white;mso-ansi-language:TR;mso-fareast-language:EN-US;mso-bidi-language: AR-SA;mso-bidi-font-weight:bold">Ailesel Akdeniz ateşi (AAA), vaskülitler, spondiloartritler, multiple skleroz ve inflamatuvar barsak hastalıkları gibi bazı sistemik inflamatuvar hastalıklar ile birliktelik gösterebilir. Ancak bu yazıda sadece vaskülitik patolojiler ile görülebilen birliktelik üzerinde durulacaktır. Aslında bu birliktelik sadece AAA olgularında vaskülitik patolojilerin sıklığının artmasından ibaret değildir; AAA olgularında vaskülit gelişme riski artmıştır. Gerçekten de, bazı yazarların da vurguladığı gibi, vaskülit AAA’nin önemli bir özelliği olabilir. AAA ile birliktelik gösterdiği belirtilen vaskülitler arasında en sık iki tanesi Henoch-Schönlein vasküliti (IgA vasküliti) ve klasik poliarteritis nodosadır; bunları uzamış febril miyalji izler. Behçet sendromu ile AAA arasında, tesadüfün ötesinde artmış bir birliktelik olup olmadığı konusu tartışmalı olmakla beraber, genel görüş bu iki hastalığın birbirinden farklı olduğu yönündedir. Bu derlemede çeşitli vaskülitik hastalıkların AAA ile birlikteliği, bu birlikteliğin altında yatan olası patojenik mekanizmalar, AAA ile ilişkili MEFV mutasyonlarının çeşitli vaskülitlerde sıklığı ve klinik önemi eldeki veriler eşliğinde tartışılmıştır.<b><span style="mso-spacerun:yes">&nbsp;&nbsp; </span></b></span><br></p>

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