Colistin in Light of Current Data
Makaleler > Tam Makale · 2012
Yazarlar: İftihar KÖKSAL, Oral ÖNCÜL, Volkan KORTEN, Sercan ULUSOY, Serhat ÜNAL
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Vol 17, Iss 4, Pp 156-160 (2012), Uluslararası, 2012
Özet
Colistin is a polypeptid antibiotic and it is used to treat infections caused by multidrug-resistant gram-negative bacteria. The intravenous use of colistin has been considered to be associated with considerable nephrotoxicity and neurotoxicity. For this reason, the systemic administration of colistin has been abandoned for about 20 years in most areas of the world. The emergence of multidrug-resistant gram-negative bacteria in parallel with the lack of new antibacterial agents led scientists to understand the importance of colistin. In this manuscript the use of colistin has been discussed in the light of current knowledge.