Therapeutic versus prophylactic plus therapeutic administration of omega-3 fatty acid on endotoxin-induced periodontitis in rats.
Articles > Article · 2004
Authors: S VARDAR, Zeki Eralp BUDUNELİ, O TURKOGLU, Afig BERDELİ, H BAYLAS, A BASKESEN, FATMA GÜL ATİLLA
JOURNAL OF PERIODONTOLOGY, Journal Indexed in SCI Expanded, International, 2004, vol 75, pp 1640-1646
DOI: 10.1902/jop.2004.75.12.1640
Summary
Background: The aim of the present study was 1) to evaluate the possible effects of therapeutic usage of omega-3 fatty acid on the gingival tissue levels of prostaglandin E-2 (PGE(2)), prostaglandin F-2alpha (PGF(2alpha)), platelet activating factor (PAF), and leukotriene B-4 (LTB4) in endotoxin-induced periodontitis in rats and 2) to investigate whether prophylactic usage provides any additional benefits to therapeutic doses of omega-3 fatty acid.