Design of 99mTc radiolabeled gemcitabine polymeric nanoparticles as drug delivery system and in vivo evaluation

Articles > Article · 2021

Authors: Çiğdem İÇHEDEF, Serap TEKSÖZ, Oguz Cetin, Burcu Aydin, Ibrahim Sarikavak, Yasemin Parlak, BEDRİYE ELVAN BİLGİN

Materials Chemistry and Physics, Journal Indexed in SCI Expanded, International, WoS, 2021, vol 263, pp 124380-124380

DOI: 10.1016/j.matchemphys.2021.124380

Summary

The main objective of this study is to create a multifunctional drug carrier system as a prototype product. For this purpose, Gemcitabine that used as an anticancer agent for several kinds of tumour therapy, and technetium(I)-tricarbonyl core, [Tc-99m(CO)(3)](+), was incorporated to the polymeric structure.

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