Cyclosporine A-induced neck fibrosis in a patient with adult-onset Still’s disease
Articles > Article · 2009
Authors: Senol Kobak, Recep SAVAŞ, Fahrettin OKSEL, EKER DOĞANAVŞARGİL
Clinical Rheumatology, Journal Indexed in SCI Expanded, International, WoS, 2009, vol 29, pp 205-208
DOI: 10.1007/s10067-009-1275-z
Summary
Cyclosporine A (CsA) is an immunosuppressive agent used for the prevention of graft rejection during organ and bone marrow transplantation. CsA is also used for the treatment of various inflammatory rheumatic diseases. Although different side effect profiles have been reported, nephrotoxicity, renal vascular damage, hypertension, and gingival hypertrophy are among the most commonly encountered side effects. The development of massive fibrosis in the neck associated with CsA in a 30-year-old male patient with Still's disease is presented herein. Significant regression was observed after the discontinuation of CsA.