Formulation and In Vitro Evaluation of Self Microemulsifying Drug Delivery System Containing Atorvastatin Calcium
Articles > Article · 2019
Authors: Mine Diril, Gülbeyaz YILDIZ TÜRKYILMAZ, Hatice Yeşim KARASULU
CURRENT DRUG DELIVERY, Journal Indexed in SCI Expanded, International, 2019, vol 16, pp 768-779
DOI: 10.2174/1567201816666190820143957
Summary
Objective: The aim of this study was to develop a new dosage form as an alternative to the classical tablet forms of atorvastatin calcium (AtrCa). The formulation strategy was to prepare an optimum self micro emulsifying drug delivery system (SMEDDS) to overcome the problem of low solubility of the active substance.