Formulation and In Vitro Evaluation of Self Microemulsifying Drug Delivery System Containing Atorvastatin Calcium
Makaleler > Tam Makale · 2019
Yazarlar: Mine Diril, Gülbeyaz YILDIZ TÜRKYILMAZ, Hatice Yeşim KARASULU
CURRENT DRUG DELIVERY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2019, cilt 16, ss 768-779
DOI: 10.2174/1567201816666190820143957
Özet
Objective: The aim of this study was to develop a new dosage form as an alternative to the classical tablet forms of atorvastatin calcium (AtrCa). The formulation strategy was to prepare an optimum self micro emulsifying drug delivery system (SMEDDS) to overcome the problem of low solubility of the active substance.