What is the Optimal Treatment for this Rare Entity: A Pediatric Case with the Hyalinizing Clear Cell Carcinoma of the Nasopharynx

Makaleler > Tam Makale · 2025

Yazarlar: Eda ATASEVEN, Sebnem Onen Goktepe, Goksel Turhal, Derya Demir, Serra Kamer, Mehmet KANTAR

JOURNAL OF PEDIATRIC RESEARCH, ESCI İndekslerine Giren Dergi, Uluslararası, Wos, 2025, cilt 12, ss 38-44

DOI: 10.4274/jpr.galenos.2024.34467

Özet

Hyalinizing clear cell carcinoma (HCCC) is a rare low-grade malignant tumorof the minor salivary glands of the head and neck. It can also arise in the nasopharynx in rare cases. Only a few cases of nasopharyngeal HCCC (NHCCC) have been reported in the literature, and most patients are in their sixth decade of life. Due to this disease's rarity, there is no consensus on its optimal treatment. Surgical excision is the mainstay of treatment. However, the role of postoperative radiotherapy is unknown. Herein, we report on a case of NHCCC in a 14-year-old female, treated successfully with sur-gical resection and adjuvant radiotherapy. This patient is the youngest case of NHCCC reported in the literature.

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