Fixed But Not Autoadjusting Positive Airway Pressure Attenuates the Time-dependent Decline in Glomerular Filtration Rate in Patients With OSA
Articles > Article · 2018
Authors: Oreste Marrone, Fabio Cibella, Jean-Louis Pepin, Ludger Grote, Johan Verbraecken, Tarja Saaresranta, John A. Kvamme, Özen KAÇMAZ BAŞOĞLU, Carolina Lombardi, Walter T. McNicholas, Jan Hedner, Maria R. Bonsignore
Chest, Journal Indexed in SCI Expanded, International, WoS, 2018, vol 154, pp 326-334
DOI: 10.1016/j.chest.2018.04.020
Summary
BACKGROUND: The impact of treating OSA on renal function decline is controversial. Previous studies usually included small samples and did not consider specific effects of different CPAP modalities. The aim of this study was to evaluate the respective influence of fixed and autoadjusting CPAP modes on estimated glomerular filtration rate (eGFR) in a large sample of patients derived from the prospective European Sleep Apnea Database cohort.