Effect of verapamil on intimal thickening and vascular reactivity in the collared carotid artery of the rabbit
Makaleler > Tam Makale · 1996
Yazarlar: L USTUNES, MUKADDER YASA, Zeliha KERRY, N OZDEMIR, T BERKAN, Y ERHAN, A OZER
BRITISH JOURNAL OF PHARMACOLOGY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 1996, cilt 118, ss 1681-1688
DOI: 10.1111/j.1476-5381.1996.tb15592.x
Özet
1 Intimal thickening is a common site for atherosclerosis. Therefore, we investigated whether the calcium entry blocker verapamil (10 mg kg(-1) body weight day(-1), s.c.) can retard intimal thickening and changes in vascular reactivity induced by a non-occlusive, silicone collar positioned around the left carotid artery of rabbits. The contralateral carotid artery was sham-operated and served as a control.