Subclinical Anterior Horn Cell Involvement in Juvenile Myoclonic Epilepsy
Makaleler > Tam Makale · 1994
Yazarlar: Cumhur Ertekin, Nilgün Araç, Safiye Bilgin, Hakan Ediboǧlu, Mustafa Ertaş
Epilepsia, Uluslararası, 1994, cilt 35, ss 322-327
DOI: 10.1111/j.1528-1157.1994.tb02438.x
Özet
Although clinical signs of muscle wasting and weakness were not present, electromyographic (EMG) evidence of subclinical anterior horn cell involvement of spinal cord was noted in 5 patients with juvenile myoclonic epilepsy (JME). Quantitative interference pattern analysis of EMG recorded from the anterior tibial muscle showed that the ratio (amplitude:turn/turn:second, A:T/T:S) was significantly increased in 10 patients with JME and 12 patients with lower motor neuron disorders (LMND) as compared with those of 22 normal subjects and 15 patients with frequent generalized tonic-clonic seizures (GTC). Subclinical anterior horn cell involvement detected by EMG techniques can be related to a genetically determined component of JME.