A rare case of giant cutaneous leiomyosarcoma: A case report
Articles > Article · 2015
Authors: Mehdi ISKANDARLI, BENGÜ GERÇEKER TÜRK, Banu YAMAN, Taner AKALIN, Can CEYLAN
TURKDERM-ARCHIVES OF THE TURKISH DERMATOLOGY AND VENEROLOGY, Journal Indexed in ESCI, International, 2015, vol 49, pp 226-228
Summary
Leiomyosarcoma (LMS) commonly arises from smooth muscles of visceral organs, such as uterus, gastrointestinal system and has a poor prognosis due to its metastatic potential. LMS derived from smooth muscles of the skin, named superficial LMS, usually indolent and has a better prognosis. Especially, LMS derived from pilar muscles is usually restricted to the dermis and rarely metastasizes. However, LMS originating from smooth muscles of subcutis behaves more aggressively and metastasizes more commonly. Here, we report a patient with giant superficial LMS on the lower extremity which invaded the underlying tissues like bone, tendons and joint and metastasized to the lung. The patient received chemotherapy following a below-knee amputation.