Hepatitis E virus IgG seroprevalence in liver transplant patients: A retrospective single-center experience
Makaleler > Tam Makale · 2021
Yazarlar: Ferit Celik, Ali Senkaya, Nalan Gülşen ÜNAL, Seymur Aslanov, Alper Uysal, Aysin Zeytinoglu, İlker TURAN, Murat Zeytunlu, Omer Ozutemiz, Ulus Salih Akarca
HEPATOLOGY FORUM, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2021, cilt 2, ss 7-11
DOI: 10.14744/hf.2020.2020.0030
Özet
Background and Aim: Hepatitis E virus (HEV) may cause chronic liver disease in solid organ transplant recipients. We determined HEV seroprevalence and associated factors in liver transplant recipients.Materials and Methods: Patients followed at the outpatient clinic of liver transplantation between January 2019 and January 2020 were screened retrospectively for HEV serology (HEV immunoglobulin M [IgM] and HEV immunoglobulin G [IgG]).Results: Of the 150 patients (male/female, 104/46; age, 55.4 +/- 13.2 years), anti-HEV IgG was positive in 31 (20.7%), and anti-HEV IgM was negative in all. The mean time after liver transplantation (72 [48%] deceased and 78 [52%] living donors) was 81 +/- 78.5 months. Drinking water consisted of carboy and tap water in 88 (58.7%) and 62 patients (41.3%), respectively. Of the patients, 120 (80%) and 30 (20%) lived in urban and rural areas, respectively. On comparison, the difference between positive and negative anti-HEV IgG groups in terms of age, place of birth, water supply, and donor type was statistically significant (p=0.007, p=0.000, p=0.034, and p=0.049, respectively).Conclusion: HEV seroprevalence was more frequent in liver transplant recipients compared with the normal population. Older age, water supply, and place of birth were risk factors for HEV seroprevalence.