The effect of continuous combined oral estradiol and norethisterone on the renal and internal carotid artery pulsatility indices in postmenopausal women
Makaleler > Tam Makale · 2000
Yazarlar: Serdar ÖZŞENER, Sermet SAĞOL, K OZTEKIN, O BILGIN
International Journal of Gynecology & Obstetrics, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2000, cilt 69, ss 281-282
DOI: 10.1016/s0020-7292(00)00182-x
Özet
Postmenopausal estrogen administration results in a marked reduction in the prevalence of cardiovascular disease, particularly coronary heart disease, an effect that does not appear to be lost when cyclical progestogen is also included. Estrogen acts directly on blood vessels through both endothelium-dependent and calcium-dependent mechanisms to improve arterial function. Not only does it have a beneficial effect on the circulating blood lipid fractions, but it is now established that estrogen has a positive influence in preventing the deposit of cholesterol in the arterial endothelium; it also induces vasodilatation, increases pe-