Renal scarring and osteopontin gene C/T polymorphism in children with primary vesicoureteral reflux

Articles > Article · 2011

Authors: Hakan Erdogan, Sevgi Mir, Afig BERDELİ, Nejat Aksu

Indian Pediatrics, Journal Indexed in SCI Expanded, International, WoS, 2011, vol 49, pp 311-313

DOI: 10.1007/s13312-012-0038-0

Summary

We examined for osteopontin (OPN) gene C/T polymorphism in 78 patients (53 girls) with vesicoureteric reflux, with or without renal scarring. The T allele frequency was associated with a significantly increased risk (26.4 fold) of renal scarring.

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