Community-acquired pneumonia due to S. aureus
Bildiriler > Özet Bildiri
Yazarlar: Sinem Ozsari, Pinar Sarac, Mehmet Sezai TAŞBAKAN, Abdullah SAYINER
European Respiratory Journal, , , Uluslararası, Özet Bildiri, Wos, cilt 38, ss p2465-p2465
DOI: 10.1183/13993003/erj.38.suppl_55.p2465
Özet
Introduction and aim: Methicillin resistant S. aureus (MRSA) is an important cause of hospital-acquired pneumonia. There is little data regarding its association with community-acquired pneumonia (CAP). This study aimed to evaluate the risk factors and clinical course of CAP caused by MRSA and methicillin-susceptible S.aureus (MSSA). Material and method: Forty-eight pneumonia cases that were followed up in a tertiary care center between September 2008 - September 2010 and in whom MRSA or MSSA was isolated from initial respiratory specimens were analyzed. Findings: MRSA was isolated in 19 and MSSA in 29 of 48 cases (38 male, mean age 61.5±17.9). Risk factors for health-care-associated pneumonia (HCAP) (33 vs 16%, p<0.0001), history of hospitalization (29 vs 22%, p=0.016), surgical intervention (12 vs 4%, p=0.033) and admission to intensive care unit (14 vs 4%, p=0.014) in the preceding three months were more common in cases with MRSA pneumonia. Length of stay in the intensive care unit (11.5±4.1 vs 2.7±0.8 days, p=0.048) and in the hospital (23.1±4.1 vs 13.9±1.6 days, p=0.049) were longer in cases with MRSA pneumonia. There was no significant difference in mortality between the two groups (31.6 vs 37.9%). Three MRSA pneumonia cases without risk factors for healthcare-associated pneumonia were diagnosed as community-acquired MRSA (CA-MRSA) pneumonia. The latter cases were found to be older, this difference not reaching statistical significance (76.3±7.2, p=0.093). There was no difference in the other clinical and biochemical parameters. Conclusion: HCAP and CAP caused by S. aureus is associated with significant mortality and morbidity. There are too few cases to better define CA-MRSA pneumonia.