Prevalence and Clinical Associations of Malnutrition and Sarcopenia Risk in Gastroenterology Inpatients: A Multicenter Cross-Sectional Study in Turkey
Makaleler > Tam Makale · 2025
Yazarlar: Göksel Bengi, Süleyman Dolu, Yavuz Özden, Nevin ORUÇ, Mukaddes Tozlu, Gözde Derviş Hakim, Genco Gençdal, Ali Rıza Çalışkan, Müge Ustaoğlu, Ufuk Kutluana, Engin Altıntaş, Galip Egemen Atar, Ahmet Uyanıkoğlu, Sezgin Barutçu, Kader Irak, Deniz Koç, Berat Ebik, Züleyha Akkan Çetinkaya, Haluk Tarık Kani, Dilek Oğuz, Filiz Araz, Altay Kandemir, Nermin Mutlu Bilgiç, Özdal Ersoy, Özlem Gül, Banu Kara, Burak Özşeker, Hüseyin Alkım, Sedat Boyacıoğlu, Ayşe Kefeli, Hasan Yılmaz, Pembe Keskinoğlu, Yasemin Gökden Gök, Çağlayan Keklikkıran, Müjde Soytürk, Salih Tokmak, Murat Aladağ, Hakan Ünal, Funda Uğur Kantar, Yusuf Serdar Sakin, Meral Kayhan, Ozan Cengiz, Tolga Gözmen, İsmail Atasoy, Hale Akpınar
Diagnostics, Uluslararası, Wos, 2025, cilt 15, ss 2935-2935
DOI: 10.3390/diagnostics15222935
Özet
Background/Objectives: This study aimed to determine the prevalence of malnutrition and sarcopenia risk among patients hospitalized in gastroenterology clinics across different geographical regions of Turkey, to identify their risk factors, and to evaluate their associations with clinical outcomes. Methods: A total of 1051 patients admitted to 36 gastroenterology clinics across six geographical regions of Turkey during the week of 14 November 2024 were evaluated in a cross-sectional design. The nutritional status of the patients was assessed using the NRS-2002 questionnaire, while the risk of sarcopenia was evaluated with the SARC-F questionnaire. Demographic data, clinical diagnoses, disease severity scores, and comorbidities were also recorded and analyzed. Results: Of the patients included in the study, 54.7% were female, and the mean age was 61.7 ± 17.2 years. The prevalence of malnutrition risk was 27.8%, while the prevalence of sarcopenia risk was 32.7%. Patients with malnutrition risk had a lower BMI (24.7 ± 5.3 vs. 27.1 ± 5.4, p < 0.001) and were older (67.6 ± 16.0 vs. 56.5 ± 17.1, p < 0.001). The risks of sarcopenia and malnutrition were significantly higher in patients with liver cirrhosis (40.7% malnutrition; 54.5% sarcopenia), gastrointestinal malignancy (50.5%; 44.2%), and diabetes mellitus. Logistic regression analysis identified older age, male sex, and presence of malignancy as independent risk factors for malnutrition, whereas older age, female sex, presence of malnutrition, liver cirrhosis, and heart failure were independent risk factors for sarcopenia. A strong correlation was also found between malnutrition and sarcopenia (r = 0.544, p < 0.001). Conclusions: Approximately one-third of patients hospitalized in gastroenterology clinics across Turkey are at risk of malnutrition and sarcopenia. These conditions are particularly associated with malignancy, cirrhosis, and metabolic comorbidities. Our findings highlight the necessity of systematic nutritional and sarcopenia screening upon hospital admission.