Cycloartane-type glycosides from Astragalus brachycalyx FISCHER and their effects on cytokine release and hemolysis
Articles > Article · 2017
Authors: Behnaz ASLANIPOUR, Derya GÜLCEMAL, Ayşe NALBANTSOY, Hasan YUSUFOGLU, Erdal Bedir
Phytochemistry Letters, Journal Indexed in SCI Expanded, International, WoS, 2017, vol 21, pp 66-73
DOI: 10.1016/j.phytol.2017.05.028
Summary
Two new tridesmosidic cycloartane-type triterpene glycosides (1 and 2) were isolated from the methanolic extract of the roots of Astragalus brachycalyx FISCHER (A. brachycalyx) along with ten (3-12) known cycloartanetype triterpene glycosides. Structures of the new compounds were established as 3-O-beta-D-xylopyranosyl-6-O-beta-Dglucopyranosyl- 16-O-beta-D-glucopyranosyl-3 beta, 6a, 16 beta, 24(S)-25-pentahydroxycycloartane (1), 3-O-[a-L-arabinopyranosyl-(1. 2)-beta-D-xylopyranosyl]-6-O-beta-D-glucopyranosyl-16-O-beta-D-glucopyranosyl-3 beta, 6 alpha, 16 beta, 24(S)-25-pentahydroxycycloartane (2), by using 1D and 2D-NMR techniques and mass spectrometry.