Study for the Diagnostic Screening of Paroxysmal Nocturnal Hemoglobinuria in Older Patients with Unexplained Anemia and/or Cytopenia
Articles > Article · 2020
Authors: Zehra N. Ozdemir, OSMAN İLHAN, Gulsum Ozet, Mesude Falay, Mustafa Yenerel, Tulin Tuglular, Mehmet Turgut, BİROL GÜVENÇ, ALİ ÜNAL, Orhan Ayyildiz, NESLİHAN ANDIÇ, Abdullah Hacihanefioglu, Fahri ŞAHİN, MEHMET ŞENCAN, RIDVAN ALİ, GÜNER HAYRİ ÖZSAN, Rahsan Yildirim, EYÜP NACİ TİFTİK, ANIL TOMBAK, OZAN SALİM, EMİN KAYA, Olga M. Akay, Vahap Okan, MUSTAFA PEHLİVAN, Güray SAYDAM
CLINICAL LABORATORY, Journal Indexed in SCI Expanded, International, 2020, vol 66, pp 1709-1715
DOI: 10.7754/clin.lab.2020.191218
Summary
Background: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematopoietic stem cell disease that may lead to weakness and death of patients, if unrecognized and untreated. Although consensus guidelines were reviewed recently for the diagnostic screening of PNH with multi-parameter flow cytometry (FCM), until now, no study has investigated the efficiency of such clinical indications in older patients.