Flow Cytometry and Annexin V Marking Results
Makaleler > Tam Makale · 2023
Yazarlar: Ceren Gonen
International Journal of Science and Research (IJSR), Uluslararası, 2023, cilt 12, ss 942-947
Özet
Prostate cancer is an androgen-dependent cancer that initially develops.In this context, the first protocol of treatment consists of androgen deprivation therapy.Initially, cells that respond well to this treatment gain resistance after a while and begin to grow independently of androgen.The effects of androgens are mediated by the androgen receptor (AR).Therefore, studies focus on identification of AR regulated genes that are also highly expressed in the prostate.STAMP family genes STAMP1/ STEAP2 and STAMP2/STEAP4 are only expressed in androgen receptor positive cells Flow cytometer was used and annex in V signal were taken per sample. Significance StatementAs you will see the Annex in V signal at all samples of the paper, flow cytometer is the ideal method for apoptosis identification.