Multiple Unrelated Malignancies Following Renal Transplantation: An Evaluation of Four Cases
Articles > Article · 2013
Authors: Erhan TATAR, Banu SARSIK KUMBARACI, Ozkan GUNGOR, Banu YAMAN, Nazan ÖZSAN, Seckin CAGIRGAN, Meltem SEZİŞ, Taylan Özgür SEZER, Cuneyt HOŞCOŞKUN, Hüseyin TÖZ
INTERNAL MEDICINE, Journal Indexed in SCI Expanded, International, 2013, vol 52, pp 673-677
DOI: 10.2169/internalmedicine.52.8591
Summary
The risk of de novo malignancy is significantly higher in patients who have undergone organ transplantation than in the general population. Long-term immunosuppressive treatment, in addition to age, genetic pre-disposition and infectious agents, plays a major role in the development of malignancy. Although skin and hemopoietic system cancers are common, atypical presentations of malignancies may occasionally be seen during long-term follow-up in patients with functioning allografts. In this report, four cases, each with more than one different primary malignancy (one patient with three malignancies and three patients with two malignancies), are presented.