Gingival Crevicular Fluid Levels of Cathelicidin LL-37 and Interleukin-18 in Patients With Chronic Periodontitis

Articles > Article · 2009

Authors: Hatice Oya TÜRKOĞLU, Gülnur EMİNGİL, Necil KÜTÜKÇÜLER, FATMA GÜL ATİLLA

JOURNAL OF PERIODONTOLOGY, Journal Indexed in SCI Expanded, International, 2009, vol 80, pp 969-976

DOI: 10.1902/jop.2009.080532

Summary

Background: Cathelicidin LL-37, an antimicrobial peptide, is part of the host innate immune response in the oral cavity. Interleukin (IL)-18, a proinflammatory cytokine, could play a role in the progression of the inflammatory response. The aim of the present study was to determine the levels of cathelicidin LL-37 and IL-18 in the gingival crevicular fluid (GCF) of patients with gingivitis and chronic periodontitis.

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