Antimicrobial and antioxidant activities of Porphyridium Cruentum
Makaleler > Tam Makale · 2017
Yazarlar: Fethiye Ferda YILMAZ, Zeliha DEMİREL, Nefise Ülkü KARABAY YAVAŞOĞLU, Güven ÖZDEMİR, Meltem Conk-Dalay
HACETTEPE UNIVERSITY JOURNAL OF THE FACULTY OF PHARMACY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Scopus, 2017, cilt 37, ss 1-8
Özet
In the present study, it was aimed to cultivate and analyze the potential antimicrobial and antioxidant activity of Porphyridium cruentum. The biomass achieved from P. cruentum cultures was processed to obtain ethanol, n-hexane, methanol extracts and volatile components. Antimicrobial, antioxidant activities and total phenolic contents of the extracts were investigated by in vitro test methods. In addition, volatile compounds of P. cruentum were elucidated by GC/GC-MS. When compared to the other solvent extracts, a potential antimicrobial activity was observed only in the n-hexane extract. Besides, it showed the best activity against Staphylococcus aureus ATCC 6538P. Volatile parts were active only against Pseudomonas aeruginosa ATCC 27853. The highest amount of total phenolic compounds was found as 62.45±2.0 mg Gallic Acid Equivalent/g Dry Weight (mgGAE/gDW) in the n-hexane extract. Statistically, a remarkable correlation was established between radical scavenging capacities and the total phenolic contents of the ethanol extracts. The level of antioxidant capacities varied according to the test methods. Consequently, it was thought that P. cruentum could be considered as an important origin of natural compounds and a strong alternative to the other natural sources such as higher plants, because of potentially valuable antioxidant, antimicrobial constutients.