Effect of prolonged administration of bovine lactoferrin in neuropathic pain: Involvement of opioid receptors, nitric oxide and TNF-alpha

Articles > Article · 2010

Authors: Aytuel Onal, Gülgün ŞENGÜL, Ayse Parlar, Ayşegül KESER, Sibel Ulker

LIFE SCIENCES, Journal Indexed in SCI Expanded, International, 2010, vol 86, pp 251-259

DOI: 10.1016/j.lfs.2009.12.007

Summary

Aims: This study aimed to investigate the effect of prolonged administration of bovine milk lactoferrin (bLF) on hyperalgesia and allodynia in a rat model of neuropathic pain and to determine the involvement of c-Fos, TNF-alpha, nitric oxide and opioidergic systems in this effect.

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