Haemophagocytic lymphohistiocytosis in a patient with left ventricular assist device

Articles > Editorial · 2021

Authors: Defne Güneş ERGİ, Ander Dorken Gallastegi, Eren Arslan, Ümit KAHRAMAN

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, Journal Indexed in SCI Expanded, International, 2021, vol 60, pp 717-718

DOI: 10.1093/ejcts/ezab102

Summary

Left ventricular assist devices provide circulatory support to heart failure patients while awaiting a suitable donor heart. However, with their increased duration of therapy, complications are seen frequently. Although coagulation disorders (bleeding and thrombosis) are the most common complications, infection is also a major complication associated with significant morbidity. We report a case of a 53-year-old male with a left ventricular assist device who presented with driveline infection. He subsequently developed pancytopenia and was diagnosed with haemophagocytosis. Immediate treatment with intravenous immunoglobulin and methylprednisolone was started. His blood cell count returned to normal levels and the patient became eligible for heart transplantation again. Our case represents the rare occurrence of haemophagocytosis in a patient, which, if unnoticed, could lead to fatal consequences.

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