Scintigraphic imaging with a peptide glucuronide in rabbits: 99mTc- exorphin C glucuronide
Articles > Article · 2006
Authors: TÜRKAN ERTAY, Perihan ÜNAK, Fazilet Zümrüt BİBER MÜFTÜLER, CENGİZ TAŞÇI, Figen ZİHNİOĞLU, HATİCE DURAK
Applied Radiation and Isotopes, Journal Indexed in SCI Expanded, International, WoS, 2006, vol 65, pp 170-175
DOI: 10.1016/j.apradiso.2006.03.017
Summary
A peptide glucuronide (Exorphin C glucuronide) was labeled with Tc-99m using glucoheptonate (GH) as a bifunctional chelating agent. Scintigraphic imaging was performed in male Albino rabbits. Exorphin C glucuronide showed rapid and efficient labeling with Tc-99m using glucoheptonate as a bifunctional chelate. Results demonstrated that Tc-99m-GEG may be a useful new type of glucuronide derivative of peptides for diagnosis of some cancer diseases. (c) 2006 Elsevier Ltd. All rights reserved.