Scintigraphic imaging with a peptide glucuronide in rabbits: 99mTc- exorphin C glucuronide

Makaleler > Tam Makale · 2006

Yazarlar: TÜRKAN ERTAY, Perihan ÜNAK, Fazilet Zümrüt BİBER MÜFTÜLER, CENGİZ TAŞÇI, Figen ZİHNİOĞLU, HATİCE DURAK

Applied Radiation and Isotopes, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2006, cilt 65, ss 170-175

DOI: 10.1016/j.apradiso.2006.03.017

Özet

A peptide glucuronide (Exorphin C glucuronide) was labeled with Tc-99m using glucoheptonate (GH) as a bifunctional chelating agent. Scintigraphic imaging was performed in male Albino rabbits. Exorphin C glucuronide showed rapid and efficient labeling with Tc-99m using glucoheptonate as a bifunctional chelate. Results demonstrated that Tc-99m-GEG may be a useful new type of glucuronide derivative of peptides for diagnosis of some cancer diseases. (c) 2006 Elsevier Ltd. All rights reserved.

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