Acetatobis( l -arginine)copper( ii ) acetate trihydrate: synthesis from l -argininium acetate, structural-electronic insights and in vitro antimicrobial activity

Articles > Article ยท 2026

Authors: Amani Direm, Salima Samai, Hamza Athmani, Mohammed S. M. Abdelbaky, Cemal PARLAK, Olufunso Abosede, Santiago Garcia-Granda, Ponnadurai Ramasami

RSC Advances, Journal Indexed in SCI Expanded, International, WoS, 2026, vol 16, pp 50793-50805

DOI: 10.1039/d6ra03860c

Summary

antimicrobial assays against a panel of pathogenic bacterial and fungal strains. The results demonstrate significant inhibitory activity, suggesting that the integration of the bioactive l-arginine moiety with the copper(ii) centers may lead to enhancing the pharmacological profile of the precursor. This work provides a structural and theoretical framework for the development of arginine-based metal complexes as candidates for next-generation antimicrobial drugs.

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