THE ROLE OF IMAGE DERIVED RISK FACTORS (IDRF) IN NEUROBLASTOMA SURGERY
Bildiriler > Tam Metin Bildiri · 2023
Yazarlar: Hilmican Ulman, Egemen Öztürk, Ahmet ÇELİK, Bengü Demirağ, Deniz Kızmazoğlu, Ülküm Zafer DÖKÜMCÜ, Yeşim ERTAN, Eda ATASEVEN, Hatice Nur Olgun
24th European Paediatric Surgeons’ Association Congress, Türkiye, İzmir, Uluslararası, Poster, Tam Metin Bildiri, 2023-2023, ss 289-289
Özet
<p><strong>THE ROLE OF IMAGE DERIVED RISK FACTORS (IDRF) IN NEUROBLASTOMA SURGERY</strong></p><p><strong>Hilmican Ulman, Egemen Öztürk, Eda Ataseven, Bengü Demirağ, Deniz Kızmazoğlu, Zafer Dökümcü, Yeşim Ertan, Nur Olgun, Ahmet Çelik</strong></p><p><strong>Aim of the Study: </strong>To reveal the effect of Image Derived Risk Factors (IDRF) on the long-term results of the surgical treatment of neuroblastic tumors.</p><p><strong>Methods:</strong> The patients operated for neuroblastoma in our center between January 2003 and June 2020 were included. The cross-sectional images of the patients were re-evaluated by a single radiologist for IDRFs. Surgical and oncological data were gathered retrospectively.</p><p><strong>Main Results:</strong> IDRFs of 137 neuroblastoma and 13 ganglioneuroblastoma patients (n=150) were evaluated. The most common IDRF was renal pedicle invasion and the chemosensitivity of individual IDRFs were diverse. Mean number of IDRFs per patient dropped from 2,1 to 1,4 with chemotherapy (p<.0001). With chemotherapy, 17 (21.5%) patients became IDRF-negative, while a partial decline was observed in 39 (49.4%). No new IDRF arose during chemotherapy. IDRFs most sensitive to chemotherapy were spinal canal infiltration, and involvement of SMA branches. Complications: need for blood transfusion (18.0%), chylothorax (2.7%), nephrectomy (2.7%), massive bleeding (0.7%), transient Horner's syndrome (0.7%), vascular injury repaired primarily (5.2%). Pre-operative IDRFs were associated with surgical complications (p=.033). Presence of IDRF at diagnosis and pre-operatively was associated with lower survival (p=.01). Vascular type IDRFs were found to be the type with the most negative impact on survival. Complete resection was performed in all patients (100%) who underwent minimally invasive surgery. </p><p><strong>Conclusions:</strong> IDRFs and other prognostic factors can be used to predict long-term outcomes and possible complications in the surgical treatment of neuroblastic tumors. Minimally invasive surgery is safe and effective in IDRF-negative patients.</p><p><strong>Keywords: </strong>Neuroblastoma; IDRF; Intraoperative Complications; Risk Factors; Prognosis; Child</p><p><br></p>