Human Papilloma Virus‐11 DNA Detection by Graphene‐PAMAM Modified Impedimetric CRISPR‐dCas9 Biosensor
Makaleler > Tam Makale · 2021
Yazarlar: Mehmet Utku Mumcu, Hilmiye Deniz Ertuğrul Uygun, Zihni Onur Uygun
Electroanalysis, Uluslararası, Wos, 2021, cilt 34, ss 830-834
Özet
Abstract Human Papilloma Virus‐11 (HPV‐11) is leads to condylomata acuminata (CA), which has commonly known as genital wards that global widespread incidence of 160 to 289 cases per year. In the first‐time literature, we detect HPV‐11 DNA by using dCas9 modified graphene oxide‐PAMAM modified electrodes, impedimetrically. Chronoimpedimetric detection was facilitated the biosensor response time optimization of HPV‐11 DNA in 5 minutes. The biosensor has ability to analyze HPV‐11 DNA between 50 pM and 1000 pM with good linearity, sensitivity and selectivity. Moreover, we tested our biosensor in real samples matrix by considering recovery of the samples.