Effects of Dietary Carbohydrate Concentration and Glycemic Index on Blood Glucose Variability and Free Fatty Acids in Individuals with Type 1 Diabetes
Makaleler > Tam Makale · 2024
Yazarlar: Selda Seçkiner, Murat Baş, Ilgın YILDIRIM ŞİMŞİR, Su ÖZGÜR, Yasemin AKÇAY, Çiğdem Gözde Aslan, Özge KÜÇÜKERDÖNMEZ, Şevki ÇETİNKALP
NUTRIENTS, SCI İndekslerine Giren Dergi, Uluslararası, Scopus, 2024, cilt 16, ss 1383-1395
DOI: 10.3390/nu16091383
Özet
<p>Monitoring glycemic control status is the cornerstone of diabetes management. This study aimed to reveal whether moderate-carbohydrate (CHO) diets increase the risk of free fatty acid (FFA) levels, and it presents the short-term effects of four different diet models on blood sugar, glycemic variability (GV), and FFA levels. This crossover study included 17 patients with type 1 diabetes mellitus to identify the effects of four diets with different CHO contents and glycemic index (GI) on GVandplasma FFA levels. Diet 1 (D1) contained 40% CHO with a low GI, diet 2 (D2) contained 40% CHOwithahighGI,diet 3 (D3) contained 60% CHO with a low GI, and diet 4 (D4) contained 60% CHOwithahighGI.Interventions were performed with sensor monitoring in four-day periods and completed in four weeks. No statistical difference was observed among the groups in terms of blood glucose area under the curve (p = 0.78), mean blood glucose levels (p = 0.28), GV (p = 0.59), and time in range (p = 0.567). FFA and total triglyceride levels were higher in the D1 group (p < 0.014 and p =0.002, respectively). Different diets may increase the risk of cardiovascular diseases by affecting GI, FFA, and blood glucose levels.</p>