An Unusual Presentation of Anti-Jo-1 Syndrome, Mimicking Lung Metastases, With Massive Pleural and Pericardial Effusions

Articles > Article · 2006

Authors: Nesrin MOĞULKOÇ BISHOP, Yasemin KABASAKAL, Pervin KORKMAZ, Pw Bıshop

JCR: Journal of Clinical Rheumatology, Journal Indexed in SCI Expanded, International, WoS, 2006, vol 12, pp 90-92

DOI: 10.1097/01.rhu.0000209894.43413.67

Summary

In Brief We report a case of anti-Jo-1 syndrome (a rare autoimmune condition that may manifest with various forms of interstitial lung disease), which in our case presented unusually with multiple pulmonary nodules, mimicking carcinoma. She subsequently developed pleural and pericardial effusions (which are rare in this syndrome), myopathy, and “mechanic's hand,” with similar lesions on the feet. “Mechanic's foot” noted in this patient has not been previously described. She initially responded well to immunosuppression but has subsequently progressed to pulmonary fibrosis. Dramatic pulmonary nodules and effusions caused concern about malignancy. The patient eventually developed mechanic's hands and feet, and improved with corticosteroids.

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