Fas/FasL gene polymorphism in patients with Hashimoto’s thyroiditis in Turkish population
Articles > Article · 2016
Authors: Mehmet ERDOĞAN, M. Kulaksizoglu, SENCER GANİDAĞLI, Afig BERDELİ
Journal of Endocrinological Investigation, Journal Indexed in SCI Expanded, International, WoS, 2016, vol 40, pp 77-82
DOI: 10.1007/s40618-016-0534-5
Summary
Objective Hashimoto's disease is a polygenic disorder with complex etiopathogenesis. Apoptosis is proposed as one of its mechanisms. The Fas/Fas ligand cascade represents a major pathway initiating apoptosis. This study aims to evaluate the influence of Fas and FasL gene polymorphism in Hashimoto's thyroiditis in Turkish population.