Assessment of Ventricular Functions by Tissue Doppler Echocardiography in Follow-up of Patients with Kawasaki Disease
Makaleler > Tam Makale · 2026
Yazarlar: Mustafa Orhan Bulut, Murat Deveci, Bedir Akyol, Zülal Ülger, Reşit Ertürk LEVENT, Arif Ruhi Özyürek
Journal of Dr Behcet Uz Children s Hospital, Uluslararası, 2026, cilt 16, ss 91-97
DOI: 10.4274/jbuch.galenos.2026.22800
Özet
Objective: To evaluate ventricular functions using tissue Doppler echocardiography in long-term followup of children with Kawasaki disease after acute phase treatment.Method: Thirty patients (16 boys, 14 girls; mean age 4.41±3.07years) treated for Kawasaki disease at our unit between September 1999 and June 2009 were compared with 24 healthy controls of similar age and gender.All subjects underwent standard and tissue Doppler echocardiographic evaluations.Systolic (S') and diastolic (E', A') myocardial velocities were measured from left ventricular basal segments, and myocardial performance indices (MPIs) were calculated.Results: Mean follow-up period was 24.53±19.06months.Coronary artery involvement occurred in 13 (43.3%)patients during acute phase, but no aneurysms persisted during follow-up period.Standard echocardiographic parameters including left ventricular ejection fraction, shortening fraction, mitral flow velocities, and aortic velocity showed no significant differences between groups (p>0.05).Tissue Doppler echocardiography measurements of lateral wall velocities and time intervals were comparable.However, left ventricular MPIs were significantly higher in patients (0.518±0.028) compared to controls (0.497±0.028) (p=0.01).Conclusions: Despite normal conventional echocardiography findings after average 2-year follow-up period, elevated myocardial performance indices indicated subclinical global ventricular dysfunction in children with Kawasaki disease.Tissue Doppler-derived MPI represents a valuable non-invasive parameter for long-term cardiac surveillance in these patients.