Tryptamine derived amides with thiazole ring system from Thermoactinomyces strain TA66‐2
Articles > Article · 2007
Authors: Cagla Akmemıs Korkmaz, Elif Esin HAMEŞ, Ataç UZEL, Erdal Bedir
Magnetic Resonance in Chemistry, Journal Indexed in SCI Expanded, International, WoS, 2007, vol 46, pp 80-83
DOI: 10.1002/mrc.2101
Summary
A moderately thermophilic actinomycete strain, which was identified as Thermoactinomyces strain TA66-2, was isolated from hot-spring water. Fermentation, followed by solvent partition and chromatographic separations, resulted in the isolation of two new and two known molecules. The structures of the new compounds were elucidated as 2-(1-Propionylaminoethyl)thiazole-4-carboxylic acid [2-(1H-indol-3-yl)ethyl]amide and 2-(1-Acetylaminoethyl)thiazole-4-carboxylic acid [2-(1H-indol-3-yl)-ethyl]amide by using spectral methods (1D-, 2D-NMR and LC-ESI-MS).