Triterpene saponins from Nigella sativa L.

Articles > Article · 2005

Authors: MK Taskin, Özgen ALANKUŞ, H Anil, H Abou-Gazar, IA Khan, E Bedir

TURKISH JOURNAL OF CHEMISTRY, Journal Indexed in SCI Expanded, International, 2005, vol 29, pp 561-569

Summary

Three known triterpene glycosides were isolated from the MeOH extract of dried and powdered seeds of Nigella sativa. The structures of the compounds were established as 3-O-[beta-D-xylopyranosyl-(1 -> 3)-alpha-L-rhamnopyranosyl-(1 -> 2)-alpha-L-arabinopyranosyl]-28-O-[alpha-L-rhamnopyranosyl-(1 -> 4)-beta-D-glucopyranosyl-(1 -> 6)-beta-D-glucopyranosyl]-hederagenin (1), 3-O-[alpha-L-rhamnopyranosyl-(1 -> 2)-alpha-L-arabinopyranosyl]-28-O-[alpha-L-rhamnopyranosyl-(1 -> 4)-beta-D-glucopyranosyl-(1 -> 6)-beta-D-glucopyranosyl]-hederagenin (2), and 3-O-[beta-D-xylopyranosyl-(1 -> 3)-alpha-L-rhamnopyranosyl-(1 -> 2)-alpha-L-arabinopyranosyl]-hederagenin (3) by means of chemical and spectral methods. Compound 2 was isolated for the first time from the genus Nigella.

View details