Vitamin D Deficiency Prevalence in Late Neonatal Hypocalcemia: A Multicenter Study

Makaleler > Tam Makale · 2021

Yazarlar: Gulcan Seymen-Karabulut, AYLA GÜNLEMEZ, AYŞE SEVİM GÖKALP, Sukru Hatun, Fatma Kaya Narter, Mehmet Mutlus, Sebnem Kader, Demet TEREK, Deniz Hantas, EMEL OKULU, Leyla Karadeniz, H. Gozde Kanmaz Kutman, Aysegul Zenciroglu, Ozmert M. A. Ozdemir, Dilek Sarici, Muhittin Celik, Nihat Demir, Ozden Turan, Kiymet Celik, Fatih Kilicbay, Sinan Uslu, Sara Erol, Sabahattin Ertugrul, Ilkay Er, Hasan Tolga Celik, Merih Cetinkaya, Filiz Akurk-Acar, Yakup Aslan, Gaffari Tunc, Omer Guran, Ayse Engin Arisoy

Journal of Clinical Research in Pediatric Endocrinology, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2021, cilt 13, ss 384-390

DOI: 10.4274/jcrpe.galenos.2020.2021.0169

Özet

What is already known on this topic? What this study adds?Late neonatal hypocalcemia (LNH) occurs after the first 72 hours and the most common causes include excessive phosphate intake, hypomagnesemia, hypoparathyroidism, and vitamin D deficiency.Maternal vitamin D deficiency was found to be the most common cause of LNH in our study.Due to the immaturity of regulating factors of parathyroid hormone (PTH) and calcium, serum intact PTH levels may not reach expected levels and serum phosphorus levels may remain high in vitamin D deficient neonates, posing a diagnostic dilemma by mimicking primary hypoparathyroidism.

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