G protein beta 3 subunit gene polymorphism in Turkish hypertensives

Articles > Article · 2008

Authors: Emin Alioglu, Ertugrul Ercan, Istemihan Tengiz, Ahmet Yildiz, Ugur Oensel Tuerk, Serkan Saygi, F. Sirri Cam, Afig BERDELİ

ANADOLU KARDIYOLOJI DERGISI-THE ANATOLIAN JOURNAL OF CARDIOLOGY, Journal Indexed in SCI Expanded, International, 2008, vol 8, pp 331-335

Summary

Objective: G protein is one of the most important regulators of intracellular signaling pathways. C825T polymorphism of G protein (33 subunit is associated with increased intracellular signal transduction. The 825T allele has been found associated with a variety of cardiovascular risk factors, including hypertension. The aim of the present study was to investigate the association between the C825T polymorphism of the G protein beta 3 subunit and essential hypertension in Turkish population.

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