G protein beta 3 subunit gene polymorphism in Turkish hypertensives
Makaleler > Tam Makale · 2008
Yazarlar: Emin Alioglu, Ertugrul Ercan, Istemihan Tengiz, Ahmet Yildiz, Ugur Oensel Tuerk, Serkan Saygi, F. Sirri Cam, Afig BERDELİ
ANADOLU KARDIYOLOJI DERGISI-THE ANATOLIAN JOURNAL OF CARDIOLOGY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2008, cilt 8, ss 331-335
Özet
Objective: G protein is one of the most important regulators of intracellular signaling pathways. C825T polymorphism of G protein (33 subunit is associated with increased intracellular signal transduction. The 825T allele has been found associated with a variety of cardiovascular risk factors, including hypertension. The aim of the present study was to investigate the association between the C825T polymorphism of the G protein beta 3 subunit and essential hypertension in Turkish population.