Nickel-catalyzed alkylation of ketones and nitriles with primary alcohols
Makaleler > Tam Makale · 2022
Yazarlar: Sertaç Genç, Burcu Arslan, Derya GÜLCEMAL, Süleyman GÜLCEMAL, Salih GÜNNAZ
Organic & Biomolecular Chemistry, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2022, cilt 20, ss 9753-9762
DOI: 10.1039/d2ob01787c
Özet
Nickel(II)-salen or nickel(II)-salphen catalyzed α-alkylation of ketones and nitriles with primary alcohols is reported. Various α-alkylated ketones and nitriles were obtained in high yields through a borrowing hydrogen strategy by using 1-3 mol% of nickel catalyst and a catalytic amount of NaOH (5-10 mol%) under aerobic conditions.