Protective effects of minocycline on experimental spinal cord injury in rats
Articles > Article · 2015
Authors: Mustafa Aras, Murat Altas, Sedat Motor, Recep Dokuyucu, Atilla Yilmaz, Erkin ÖZGİRAY, Yurdal Seraslan, Nebi Yilmaz
Injury, Journal Indexed in SCI Expanded, International, WoS, 2015, vol 46, pp 1471-1474
DOI: 10.1016/j.injury.2015.05.018
Summary
Background: The effects of minocycline on neuronal injury after spinal cord injury (SCI) are limited and controversial. Therefore we aimed to investigate the protective effects of minocycline on tissue and on serum concentrations of malondialdehyde (MDA) levels, superoxide dismutase (SOD) activity, glutathione peroxidase (GSH-Px) activity, tissue total antioxidant and oxidant status (TAS and TOS, respectively), and AST and LDH levels in rats with SCI.