Age and gender dependent alterations in the activities of glutathione related enzymes in healthy subjects
Makaleler > Tam Makale · 2001
Yazarlar: Sara HABİF, Mehmet Işıl MUTAF, NEVBAHAR TURGAN, ECE ONUR, CAN DUMAN, DİLEK OZMEN, OYA BAYINDIR
Clinical Biochemistry, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2001, cilt 34, ss 667-671
DOI: 10.1016/s0009-9120(01)00279-x
Özet
Objectives: Oxidative stress as a result of increased free radical production is implicated in the pathogenesis of several diseases. Specific antioxidant enzymes have a crucial role in the prevention of these deleterious effects. Since the activities of these enzymes differ significantly in different populations and seem to be affected by various environmental factors, in this study we aimed to determine the reference values of glutathione related antioxidant enzyme activities in the erythrocytes of healthy subjects and to investigate the possible variations as a function of age and gender in a healthy Turkish Mediterranean population.